2017年2月7日星期二

【Common sense of kidney disease】 caused by renal damage commonly used drugs you must know Dose is t



Dose is too large, long course of treatment is the main reason for kidney damage after treatment

Medical research results show that China's kidney disease patients showed an increasing trend year by year, a large part of which is related to improper use of drugs. In the event of drug-induced renal damage, will seriously affect the patient's health, ranging from damage to kidney function, induced nephritis; weight is caused by renal necrosis, acute or chronic renal failure, serious may even cause death, must be vigilant.

Commonly used drugs to cause kidney damage are:
Such as gentamicin, kanamycin and so on. These drugs use more than 10 days, the incidence of renal damage will be significantly increased.

1
Quinolones
Such as norfloxacin, ciprofloxacin, ofloxacin and so on. Once the dose of these drugs is too large, it will cause hematuria, interstitial nephritis, severe cases can lead to acute renal failure.

2
Sulfa drugs
Such as the compound cotrimoxazole, after administration is easy to produce crystallization caused by obstructive nephropathy, hematuria, renal colic, or acute renal failure, especially in elderly patients with dehydration and more prone to. Therefore, when taking these drugs should be more water, and taking sodium bicarbonate (baking soda) tablets of urine, to reduce the damage to the kidneys.

3
Contrast media
In recent years, the application of a wide range of drugs, caused by acute renal damage is also more common. The hyperosmolarity of the contrast agent may aggravate renal ischemia and may also be directly toxic to the kidney. Because the contrast agent is allergens, can cause systemic allergic reactions involving the kidneys.

4
Chinese herbal medicine
Most people think that taking Chinese herbal medicine safe, non-toxic side effects, but in fact some of the Chinese herbal medicine due to taking excessive or contraindications in the application of the liver, kidney and other organs damage. Tripterygium wilfordii as an immunosuppressive agent, as a diuretic drug, Motherwort as a hemostatic agent, commonly used in the treatment of many diseases, but if excessive use can lead to acute renal failure.
Rhubarb as a laxative, widely used in patients with renal failure, but long-term use can cause hyperkalemia, endangering patients. In addition Kusnezoffii, Xanthium, Melia chinensis, TCS and other Chinese herbal medicine have long been due to excessive use of lead to kidney damage reported. Here solemnly reminded the elderly, especially those suffering from kidney disease in the application of Chinese herbal medicine to be extra careful.
Generally speaking, the dose is too large, long course of treatment is the main reason for kidney damage after treatment. Therefore, taking the above drugs, the first principle is to uphold the rational use of drugs, avoid drug abuse. At the same time, try to avoid two or more nephrotoxic drugs in combination, high-risk groups according to renal function to adjust the dosage and medication.

In addition, the patient must be regularly used to do renal function tests, in order to detect the early manifestations of drug-induced nephropathy. If found to have lumbar acid weakness, abnormal urine, limb swelling, fatigue, increased blood pressure and other signs of kidney disease, to be discontinued or adjust the dosage, in order to minimize the development of drug-induced nephropathy deterioration.

How to maximize kidney function in patients with renal disease?


Note that this is a stage of renal function, with the pathological grading is not a thing.

For example, some kidney friends asked, why I was IgA nephropathy Lee's 4, but the count is a chronic kidney disease, people Lee2 level, but the calculation is chronic kidney disease 2 it?

Pathological grading with renal function staging is not the same thing! Renal function staging, different types of kidney disease are in accordance with these five criteria. But the pathological classification is more complex, different types of kidney disease, assessment criteria are not the same. Pathological emphasis, renal function can be good, the pathological light side, renal function can be abnormal.

Well, understand this, we went on to say.

1 is a normal renal function, 2 of renal function mild abnormalities, 3, later, it is estimated that the glomerular filtration rate below 60ml / min / 1.73m2, can be said to renal insufficiency, 5 is us Said end-stage renal failure, which is uremic period.

So, we get to the question, how to maximize kidney Shenyou friends to delay the progress of renal function?
Control proteinuria, high blood pressure

No matter what type of kidney disease, normal renal function, or renal insufficiency, in the absence of uremia, control of urinary protein and blood pressure levels of these two aspects, are always the core of the treatment is to slow down the decline in renal function The most important measures.



Urine protein is not the lower the better, try to maintain at 0.5g / day, or 0.3g / day or less, it is very good, that treatment is very good. Some patients urine protein has zero a few grams, but also worried that they did not fully with the normal to reach 0.15g on the following uncomfortable, so that psychological, so that others urine protein a few grams of kidney friends how to do, the typical pull hatred ~

Blood pressure level is not the lower the better, blood pressure need to be controlled in the 140 / 90mmHg the following, the best state is 130 / 80mmHg the following. Less than 90 / 60mmHg is low blood pressure levels, and easily lead to insufficient renal blood perfusion, it is best not to be lower than this level. A lot of kidney friends never concerned about their blood pressure, which is not good, in the community or pharmacies with blood pressure in these places where free of charge, or home to buy a little better electronic sphygmomanometer, usually nothing to measure a volume. As now the weather is cold, high blood pressure is easy, but also to pay attention to their overall blood pressure.

For different causes and specific conditions, medication is not the same. In some cases, the use of drugs, or other drugs, or other antihypertensive drugs, some use of hormones and other immunosuppressive agents, some people are able to get some proprietary Chinese medicines can not be generalized.
Prevention and Treatment of Cardiovascular Diseases

Some people ask me, why do you say there are 120 million chronic kidney disease, but I did not see someone around? This is because the awareness of chronic kidney disease is very low, nearly 90% of people do not know that they have kidney problems.

And known to have kidney disease, know to prevent cardiovascular disease even fewer people. Some kidney friends, may not have to dialysis that step, because the cardiovascular disease game over.

Normal renal function, mild abnormal renal Friends, the incidence of cardiovascular disease than the average person much higher, with the decline in renal function, renal insufficiency, renal failure, renal disease, the incidence of cardiovascular disease is even higher . Therefore, in order to prevent "the emperor did not start a business halfway and collapse," this situation, we have a conscious prevention and treatment of cardiovascular disease.

Quit smoking, increase exercise, obese people lose weight, nutrition needs to limit the diet, malnutrition need to correct the nutritional status, which are important to improve the living habits, can help us a good prevention of cardiovascular disease. In addition, the "blood pressure, blood fat and blood sugar," the three high control is good, for existing cardiovascular disease in patients with chronic kidney disease, the doctor may recommend sustained small doses of patients with aspirin or anti-platelet drugs such as Plavix.
Complications of treatment

In stage 1-2, the complications of nephropathy are rare. And to the renal function after 3, kidney-related complications and other issues will gradually appear.

Anemia, calcium and phosphorus disorders, malnutrition, metabolic acidosis and other complications are possible, therefore, 3-4 renal function, and 5 have not been dialysis patients, control these complications, is to further deteriorate renal function .

Anemia in patients may need to use intravenous or oral iron supplementation, subcutaneous injection of synthetic erythropoietin and other treatment. Calcium and phosphorus disorders in patients with oral vitamin D, limiting high phosphorus diet, lanthanum carbonate and other phosphorus binding agents such as treatment.
Diet therapy

Inappropriate diet, such as high protein diet will accelerate the progress of kidney disease, and eat too little easily lead to malnutrition, is not conducive to rehabilitation.

Therefore, patients with kidney disease according to their own circumstances how to diet conditioning, kidney diet article wrote a lot, you can point to open these articles to see:

Got a kidney disease, diet and lifestyle conditioning summary

Low-salt diet on the original kidney patients so important? . How to control salt?

Kidney function of the kitchen | renal function 3-4, low-protein three meals a day recipes

How to understand the quality of low-protein diet?

Excessive blood phosphorus, which food can not eat? Practical method Qiao phosphorus

What to do when the doctor says you want a low-potassium diet?
Not random medication

Analgesic tablets, antibiotics, prescriptions of unknown ingredients, etc., not to mention kidney friends, is the normal kidney, eat more of these drugs, but also easy to go wrong.

In addition to some of the necessary medication, nephropathy medication must be streamlined, most of the drugs need to pass the kidney metabolism, the burden of the kidney is very heavy, especially renal toxicity of drugs.

Fatigue and infection

The two are induced and aggravated kidney disease incentives.

Not to say that every day lying on the house is not tired, the general work of the Friends of the kidney are competent, but also encourage you not always stuffy at home, in some work within its capacity. Mainly to work and rest, work and rest, do not stay up all night.

Infection, which is not to say, a proteinuria and other indicators of infection increased, it is we feel the heart plug. Usually enhance physical exercise, eat well, relax, in order to have good health, to less infection.


If with their own doctors, these areas do their best to do a good job on their own kidney baby really a clear conscience! Kidney baby you are good, kidney baby will not ill-treat you!

Patients with kidney disease can not eat soy products? What are the considerations



For many diseases, not only for end-stage renal disease, can cure is good early disease, because the general symptoms of early disease is not very obvious, the human body is very small violations, so it will be more clinically easy The treatment of some, but also in the early treatment of the disease, the probability of cure is much higher than in the late, in the early and mid-kidney disease, life considerations, especially diet considerations to control the development of the disease is very important .

01

Limit protein intake, usually about 30 grams per day. Can eat more potato, potatoes, milk, eggs, etc., eat less fish, rice.

Patients with kidney disease can not eat soy products? Beans are nutritious and close to animal proteins
Although beans are a kind of plant food, but its essential amino acids in protein, in the number and proportion are close to the animal protein. Beans food protein content of up to 35% to 40%, of which soybean protein is the best plant quality protein. Not only that, soy is also rich in calcium, phosphorus, iron and B vitamins.
Therefore: kidney disease patients can moderate consumption of legumes
Kidney disease diet should control the total intake of protein, and animal protein and vegetable protein food should be eaten together. Soybeans, large green beans and black beans and other high-quality protein, the decomposition of essential amino acids are necessary for the body to synthesize anabolic, you can eat but pay attention to the amount.
Beans should be taken as part of the total protein intake, dialysis patients should not exceed the total 1/3, so good for renal function.
Nephrotic syndrome, protein intake per day is best in about 40 to 50 grams; renal dysfunction, uremic patients and renal failure, the daily intake of plant protein and animal protein does not exceed 40 grams. If it is end-stage renal disease patients, should be more stringent restrictions.

02

Clinical diagnosis shows that uremia can be treated, even to the uremia period, but after kidney transplantation or dialysis, can return to normal family life and work, the prognosis will be better, so patients should establish confidence , To maintain an optimistic and positive confidence.

03

Kidney experts recommend that older people over the age of 65 should be checked 1-2 times per year of renal function, if the patient has been diagnosed with chronic nephritis, but also need to do regular renal function tests. Because it can develop into uremia, which is timely found that chronic uremia has a great advantage.

04

To avoid taking drugs on renal damage, so as not to promote increased renal failure.

05

Try to reduce the intensity of work, if there uremia symptoms, in addition to timely treatment, but also need bed rest.
Daily life to actively do uremia care work, neglect of nutrition therapy. Uremia is not terrible, have the right attitude to treat the disease, adhere to treatment, pay attention to diet, will restore a normal body work and life ~


Chronic kidney disease patients with end-stage dialysis should be fully under the premise of increasing the quality of protein and energy intake, due to high protein content of natural foods, but low phosphorus content of food at the same time, so dialysis friends in the selection of ingredients when the need for attention Reasonable with, try to meet the high protein and low phosphorus dietary principles, but also can select some artificial processing of low phosphorus protein supplements to meet the nutritional needs while avoiding hyperphosphatemia and calcium and phosphorus metabolism disorders and other complications, improve life quality.

Kidney disease expert analysis: more and more high creatinine, renal failure, there save it?




For most patients with kidney disease, urine protein, occult blood has almost become a "routine", but the real "meal" is caused by elevated serum creatinine after renal failure, and even uremia.



Wang Kangtong, a TCM expert in kidney medicine, said: "The most fearful of kidney disease patients is that their serum creatinine is elevated. Since the serum creatinine is elevated, most patients with kidney disease have the following feelings:
Physique is getting worse ...
More and more symptoms ...
The mood is getting worse ...
The recurrence is getting faster and faster ...
Family is getting tired ...
The family is getting poorer ...
The survival of the confidence is less and less ...
  Renal failure is caused by continuous necrosis of the nephron, renal unit necrosis, chronic renal failure is the most fundamental reason, the disease could not control, serum creatinine rose higher and higher, the development of advanced, is well-known uremia!



General treatment of renal failure is how it?
    The traditional method of treatment is injection, medication. Treatment of renal failure are the main drugs: Niaoduqing, Ai Xite, Haikun kidney-capsule, kidney failure, etc., there are many drugs, but the effect is mostly unsatisfactory.
Many patients with kidney disease have such experience: the use of these drugs, the creatinine did not decline, or even increased, and this is how is it?
Simple Western medicine treatment, there is no real down-creatinine drug, so a large part of the doctor, as long as the development of renal disease to see the three patients, directly to the patient home waiting for dialysis.
    But the dialysis will be "addictive", often a kidney disease is a lifetime, the last is useless, you have to consider for kidney, long-term dialysis, kidney transplant is very high cost, not many families can afford. Even if the first do not consider the cost of a few years for the kidney or failure again, it is only delayed renal failure time ... ... so the treatment of renal failure, really is no good way yet?

Is not no good way, but most of the kidney patients did not find the right way.
Blood creatinine in the end how should drop?
Elevated serum creatinine, because the necrotic kidney units too much, can work properly the kidney unit has been too little. But to know that there are still some of the kidney units do not work, they are not completely necrosis, but damaged. And as long as we recover this part of the kidney unit, let the normal work, renal function will increase, serum creatinine can naturally fall, which is the key to the treatment of renal failure.

The repair of kidney damage in this process, Western medicine can not be done, while the Chinese medicine is effective.


A creatinine more than 100 people, it is entirely possible by the resumption of part of the nephron, the creatinine back to normal again; and creatinine five or six hundred, or even close to uremia, but also through the recovery part of the kidney unit, part of the creatinine down, So long to maintain a stable state of creatinine, to live a normal life, is entirely possible to do, and long-term dialysis, or even kidney transplant, which is quite good.

2017年2月4日星期六

The Harm of Drinking in Nephrotic Syndrome Patients

The Harm of Drinking in Nephrotic Syndrome Patients
Nephrotic syndrome should limit drinking. Drinking can lead to increased obesity, decreased glycogen synthesis. Particularly in obese, hypertensive, nephrotic syndrome and hyperlipidemic patients. Excessive alcohol consumption can decrease appetite, food intake decreased, resulting in a variety of nutrient deficiencies, severe alcoholic cirrhosis can occur. Nephrotic syndrome patients should avoid alcohol, because alcohol can reduce renal blood flow, deterioration of renal function, and increase the burden on the heart.
Prevention of nephrotic syndrome should pay attention to infection. Nephrotic syndrome patients with low resistance, prone to infection. Patients with nephrotic syndrome should be noted that ventilation ventilation, often take a bath, keep the skin clean, to prevent urinary tract infections, pay attention to rest, cold seasonal precautions to prevent a cold, infection occurs in time for the treatment of nephrotic syndrome.


Patients with nephrotic syndrome, a small amount of alcohol is good for the body, can enhance the protection of the body against UV damage, etc., but here is a small amount of very few, about a day into a few grams of alcohol, the general amount of alcohol can not be so Less, the amount is difficult to control, so for their own health. Patients with nephrotic syndrome is best not to drink, wine can not drink, life will not cause a big impact, there is no healthy body, you can not better enjoy the beauty of life.

what can cause nephrotic syndrome

Is nephrotic syndrome harmful?
Kidney disease experts pointed out that the severity of nephrotic syndrome manifested as renal failure, uremia. In the early stages of nephrotic syndrome, if there is no effective measures to treat it, nephrotic syndrome will cause serious harm to the human body, to people's normal life and work caused a lot of inconvenience. Timely and correct treatment of the disease, so that patients get rid of nephrotic syndrome as soon as possible, with a healthy body.

When the nephrotic syndrome occurs, accompanied by nephrotic patients will occur a series of concurrent symptoms, edema, hyperlipidemia, anemia and so on. These symptoms indicate that the body resistance of patients decreased, while the body's immune regulation system has undergone tremendous changes, which will lead to abnormal expression of the body's protein, resulting in the emergence of hypoproteinemia. Nephrotic syndrome Hypoproteinemia is not only a direct impact on the body's protein needs, but also on the body there are other aspects. The human body is a complex body, its various symptoms are interrelated, mutual influence.
Due to the excretion of large amounts of proteinuria, inadequate supply of synthetic protein in the liver, leading to hypoproteinemia. The emergence of this phenomenon is a very serious nephrotic syndrome hazards. Reduce the blood protein, it will lead to decreased plasma colloid osmotic pressure, colloid osmotic pressure drop imbalance, the water will overflow within the plasma, and accumulation to the organization and body cavity, resulting in a high degree of human edema. At the same time, when the plasma water spills out, the water content in the blood decreases, and the blood volume in the active circulation is insufficient. Therefore, when the blood is reduced in water, it causes a high blood viscosity, easily forms a blood clot, Ischemia and hypoxia. The emergence of these symptoms will aggravate the process of kidney disease.


Nephrotic syndrome This disease is very high in the incidence of children in the group will have a very negative impact on the growth of children. The incidence of nephrotic syndrome is getting higher and higher, which has aroused widespread concern. Whether it can cure this disease has become one of the concerns of many patients.

What are the complications of nephrotic syndrome in children

What are the complications of nephrotic syndrome in children
Symptoms of nephrotic syndrome in children is mainly a large number of proteinuria, and then hypoproteinemia, hyperlipidemia and varying degrees of edema, edema of children with nephrotic syndrome can be both lower limb edema, nephrotic syndrome in children with common complications Disease specific description is as follows:

(1) infection: due to a large number of immunoglobulin from the urine loss, plasma protein decreased, affecting antibody formation. Adrenal cortex hormones and cytotoxic substances used, so that the patient's body resistance decreased, prone to infection, such as skin infections, primary peritonitis, respiratory infections, urinary tract infection, and even induced sepsis.

(2) coronary heart disease: pediatric nephrotic syndrome patients often hyperlipidemia and hypercoagulable state of the blood, so prone to coronary heart disease. It was reported nephrotic syndrome in patients with myocardial infarction incidence of 8 times higher than normal. Coronary heart disease has become the third cause of nephrotic syndrome death (second only to infection and renal failure).
(3) thrombosis: pediatric nephrotic syndrome in patients prone to thrombosis, in particular, the incidence of membranous nephropathy up to 25% to 40%. The formation of thrombosis due to edema, less patient activity, venous stasis, hyperlipidemia, blood viscosity increased viscosity, high levels of fibrinogen and v, Ⅶ, Ⅷ, x factor increased and the use of adrenal cortex hormones and blood-prone Hypercoagulable state.

(4) acute renal failure: children with nephrotic syndrome due to a large number of proteinuria, hypoproteinemia, hyperlipidemia, the body often in low blood volume and hypercoagulable state, vomiting, diarrhea, the use of anti-hypertensive and Diuresis diuresis, a large number of diuretic, renal blood perfusion can make a sudden decrease, thereby reducing the glomerular filtration rate, leading to acute renal failure. In addition, nephrotic syndrome, renal interstitial edema, protein concentration of tubulointerstitial tubular obstruction and other factors, can also induce acute renal failure.

(5) electrolyte and metabolic disorders: repeated use of diuretics or long-term unreasonable ban salt, can cause children with nephrotic syndrome secondary to hyponatremia; the use of adrenal cortex hormones and a large number of diuretics lead to a large number of urination, Potassium, prone to hypokalemia.


These are Xiaobian to introduce the complications of nephrotic syndrome in children, through the above complications, I hope parents and friends must learn more about nephrotic syndrome, so that early detection and early treatment, try to avoid the occurrence of these complications The harm to the child.

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