What are the complications of nephrotic syndrome in children

What are the complications of nephrotic syndrome in children

Symptoms of nephrotic syndrome in children is mainly a large number of proteinuria, and then hypoproteinemia, hyperlipidemia and varying degrees of edema, edema of children with nephrotic syndrome can be both lower limb edema, nephrotic syndrome in children with common complications Disease specific description is as follows:

(1) infection: due to a large number of immunoglobulin from the urine loss, plasma protein decreased, affecting antibody formation. Adrenal cortex hormones and cytotoxic substances used, so that the patient's body resistance decreased, prone to infection, such as skin infections, primary peritonitis, respiratory infections, urinary tract infection, and even induced sepsis.

(2) coronary heart disease: pediatric nephrotic syndrome patients often hyperlipidemia and hypercoagulable state of the blood, so prone to coronary heart disease. It was reported nephrotic syndrome in patients with myocardial infarction incidence of 8 times higher than normal. Coronary heart disease has become the third cause of nephrotic syndrome death (second only to infection and renal failure).

(3) thrombosis: pediatric nephrotic syndrome in patients prone to thrombosis, in particular, the incidence of membranous nephropathy up to 25% to 40%. The formation of thrombosis due to edema, less patient activity, venous stasis, hyperlipidemia, blood viscosity increased viscosity, high levels of fibrinogen and v, Ⅶ, Ⅷ, x factor increased and the use of adrenal cortex hormones and blood-prone Hypercoagulable state.

(4) acute renal failure: children with nephrotic syndrome due to a large number of proteinuria, hypoproteinemia, hyperlipidemia, the body often in low blood volume and hypercoagulable state, vomiting, diarrhea, the use of anti-hypertensive and Diuresis diuresis, a large number of diuretic, renal blood perfusion can make a sudden decrease, thereby reducing the glomerular filtration rate, leading to acute renal failure. In addition, nephrotic syndrome, renal interstitial edema, protein concentration of tubulointerstitial tubular obstruction and other factors, can also induce acute renal failure.

(5) electrolyte and metabolic disorders: repeated use of diuretics or long-term unreasonable ban salt, can cause children with nephrotic syndrome secondary to hyponatremia; the use of adrenal cortex hormones and a large number of diuretics lead to a large number of urination, Potassium, prone to hypokalemia.

These are Xiaobian to introduce the complications of nephrotic syndrome in children, through the above complications, I hope parents and friends must learn more about nephrotic syndrome, so that early detection and early treatment, try to avoid the occurrence of these complications The harm to the child.