Dose is too
large, long course of treatment is the main reason for kidney damage after
treatment
Medical research
results show that China's kidney disease patients showed an increasing trend
year by year, a large part of which is related to improper use of drugs. In the
event of drug-induced renal damage, will seriously affect the patient's health,
ranging from damage to kidney function, induced nephritis; weight is caused by
renal necrosis, acute or chronic renal failure, serious may even cause death,
must be vigilant.
Commonly used
drugs to cause kidney damage are:
Such as
gentamicin, kanamycin and so on. These drugs use more than 10 days, the
incidence of renal damage will be significantly increased.
1
Quinolones
Such as
norfloxacin, ciprofloxacin, ofloxacin and so on. Once the dose of these drugs
is too large, it will cause hematuria, interstitial nephritis, severe cases can
lead to acute renal failure.
2
Sulfa drugs
Such as the
compound cotrimoxazole, after administration is easy to produce crystallization
caused by obstructive nephropathy, hematuria, renal colic, or acute renal
failure, especially in elderly patients with dehydration and more prone to.
Therefore, when taking these drugs should be more water, and taking sodium
bicarbonate (baking soda) tablets of urine, to reduce the damage to the
kidneys.
3
Contrast media
In recent years,
the application of a wide range of drugs, caused by acute renal damage is also
more common. The hyperosmolarity of the contrast agent may aggravate renal
ischemia and may also be directly toxic to the kidney. Because the contrast
agent is allergens, can cause systemic allergic reactions involving the
kidneys.
4
Chinese herbal medicine
Most people
think that taking Chinese herbal medicine safe, non-toxic side effects, but in
fact some of the Chinese herbal medicine due to taking excessive or
contraindications in the application of the liver, kidney and other organs
damage. Tripterygium wilfordii as an immunosuppressive agent, as a diuretic
drug, Motherwort as a hemostatic agent, commonly used in the treatment of many
diseases, but if excessive use can lead to acute renal failure.
Rhubarb as a
laxative, widely used in patients with renal failure, but long-term use can
cause hyperkalemia, endangering patients. In addition Kusnezoffii, Xanthium,
Melia chinensis, TCS and other Chinese herbal medicine have long been due to
excessive use of lead to kidney damage reported. Here solemnly reminded the
elderly, especially those suffering from kidney disease in the application of
Chinese herbal medicine to be extra careful.
Generally
speaking, the dose is too large, long course of treatment is the main reason
for kidney damage after treatment. Therefore, taking the above drugs, the first
principle is to uphold the rational use of drugs, avoid drug abuse. At the same
time, try to avoid two or more nephrotoxic drugs in combination, high-risk
groups according to renal function to adjust the dosage and medication.
In addition, the
patient must be regularly used to do renal function tests, in order to detect
the early manifestations of drug-induced nephropathy. If found to have lumbar
acid weakness, abnormal urine, limb swelling, fatigue, increased blood pressure
and other signs of kidney disease, to be discontinued or adjust the dosage, in
order to minimize the development of drug-induced nephropathy deterioration.
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