2017年1月5日星期四
Why nephrotic syndrome always has edema
Is not showing edema, and that is representative of the patient must suffer from nephrotic syndrome. But this can not be ignored we puffiness of the prophecy, the body presents an unusual expression, the best is still more attention. So why patients with nephrotic syndrome will show swelling? Let the following hospital doctor to answer your specific.
Nephrotic syndrome, the reasons for a high degree of edema:
1, plasma colloid osmotic pressure decreased: the exchange of body fluids by osmotic pressure on both sides of the scheduling. Osmotic pressure contains the crystal osmotic pressure and the colloid osmotic pressure, the former from the crystal material (mainly electrolytes), because it can freely through the capillary wall, it is on the vascular surface humoral exchange of little effect; the latter mainly from the protein Is albumin), because it can not freely through the capillary wall, it is the main elements of vascular exchange of body fluids. Nephrotic syndrome, due to a lot of protein in the urine lost from the urine, leading to hypoproteinemia, resulting in decreased plasma colloid osmotic pressure, when the normal 3.3 ~ 4kpa down to 0.8 ~ 1.1kpa, the intravascular water to hypertonic Arrangements between the liquid movement, and episodes of edema.
2, effective blood volume reduction: plasma moisture shift to reduce the useful blood volume, which led to the following shaking the body: through the capacity of the device to make antidiuretic hormone (ADH) increased, so that renal tubular reabsorption of water added; Severe vasopressin - aldosterone system, secondary aldosteronism onset, the renal tubular reabsorption of sodium increased; inhibition of natriuretic factor, so that the reduction of renal sodium row. So the body of water, sodium retention, further exacerbated edema.
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